Scientific Publications
TGC (Transdermal Glucosamine Cream)

11. The effects of glucosamine derivatives on equine articular cartilage degradation in explant culture.
Fenton JI, Chlebek-Brown KA, Peters TL, et al.
OsteoArthritis and Cartilage. 8:444-451, 2000.

"...Our results indicate that glucosamine sulfate also has the potential to prevent or reduce articular cartilage degradation...."

PDFClick here for full abstract.
12. Glucosamine sulfate suppresses the expressions of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis.
Chu SC, Yang SF, Lue -H, et al.
Clinica Chimica Acta. 372:167-172, 2006.
13. Glucosamine oral bioavailability and plasma pharmacokinetics after increasing doses of crystalline glucosamine sulfate in man.
Persiani S, Roda E, Rovati LC, et al.
Osteoarthritis and Cartilage. 13:1041-1049, 2005.
14. Pharmaceutical and nutraceutical management of canine osteoarthritis: Present and future perspectives.
Henrotin Y, Sanchez C and Balligand M.
The Veterinary Journal. 170:113-123, 2004.
15. Recent advances in glucosamine and chondroitin supplementation.
Owens S, Wagner P and Vangsness CT Jr.
J Knee Surg. 17:185-193, 2004.
16. Glucosamine sulfate reduces osteoarthritis progression in postmenopausal women with knee osteoarthritis: evidence from two 3-year studies.
Bruyere O, Pavelka K, Rovati LC, et al.
Menopause. 11:138-143, 2004.
17. Osteoarthritic patients with high cartilage turnover show increased responsiveness to the cartilage protecting effects of glucosamine sulphate.
Christgau S, Henrotin Y, Tanko LB, et al.
Clin Exp Rheumatol. 22:36-42, 2004.
18. Medical management of osteoarthritis of the knee and hip joints.
Grainger R and Cicuttini FM.
Med J Aust. 180:232-236, 2004.
19. Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis.
Richy F, Bruyere O, Ethgen O, et al.
Arch Intern Med. 163:1514-1522, 2003.
20. Glucosamine and chondroitin sulfate: biological response modifiers of chondrocytes under simulated conditions of joint stress.
Lippiello L.
Osteoarthritis Cartilage. 11:335-342, 2003.
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